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1.
TUMORI AL CERVELLO
(BRAIN TUMORS) - Medulloblastoma and glioma Dunkel, IJ;
“High-dose chemotherapy with autologous stem cell rescue for
malignant brain tumors”; Cancer Invest. 18, 492-493; 2000.
Abrey, LE et al.; “High dose chemotherapy with autologous
stem cell rescue in adults with malignant primary brain
tumors”; J. Neurooncol. 44, 147-153; Sept., 1999 Finlay, JL;
“The role of high-dose chemotherapy and stem cell rescue in
the treatment of malignant brain tumors: a reappraisal”;
Pediatr. Transplant 3 Suppl. 1, 87-95; 1999
2.
RETINOBLASTOMA
Hertzberg H et al.; “Recurrent disseminated retinoblastoma
in a 7-year-old girl treated successfully by high-dose
chemotherapy and CD34-selected autologous peripheral blood
stem cell transplantation”; Bone Marrow Transplant 27(6),
653-655; March 2001; Dunkel IJ et al.; “Successful treatment
of metastatic retinoblastoma”; Cancer 89, 2117-2121; Nov 15
2000
3.
CANCRO DELLE OVAIE
(OVARIAN CANCER)
Stiff PJ et al.; “High-dose chemotherapy and autologous
stem-cell transplantation for ovarian cancer: An autologous
blood and marrow transplant registry report”; Ann. Intern.
Med. 133, 504- 515; Oct. 3, 2000 Schilder, RJ and Shea, TC;
“Multiple cycles of high-dose chemotherapy for ovarian
cancer”; Semin. Oncol. 25, 349-355; June 1998
4.
CARCINOMA A CELLULE MERKEL
(MERKEL CELL CARCINOMA)
Waldmann V et al.; “Transient complete remission of
metastasized merkel cell carcinoma by highdose
polychemotherapy and autologous peripheral blood stem cell
transplantation”; Br. J. Dermatol. 143, 837-839; Oct 2000
5.
CANCRO DEI TESTICOLI
(TESTICULAR CANCER)
Bhatia S et al.; “High-dose chemotherapy as initial salvage
chemotherapy in patients with relapsed testicular cancer”;
J. Clin. Oncol. 18, 3346-3351; Oct. 19, 2000 Hanazawa, K et
al.; “Collection of peripheral blood stem cells with
granulocyte-colony-stimulatin factor alone in testicular
cancer patients”;Int. J. Urol. 7, 77-82; March 2000.
6.
LINFOMA
(LYMPHOMA)
Tabata M et al.; “Peripheral blood stem cell transplantation
in patients over 65 years old with malignant
lymphoma--possibility of early completion of chemotherapy
and improvement of performance status”; Intern Med 40,
471-474; June 2001 Josting, A; “Treatment of Primary
Progressive Hodgkin’s and Aggressive Non-Hodgkin’s Lymphoma:
Is There a Chance for Cure?”; J Clin Oncol 18, 332-339;
2000; Koizumi M et al.; “Successful treatment of
intravascular malignant lymphomatosis with high-dose
chemotherapy and autologous peripheral blood stem cell
transplantation”;Bone Marrow Transplant 27, 1101-1103; May
2001
7.
LEUCEMIA LINFOCITICA ACUTA
(ACUTE LYMPHOBLASTIC LEUKEMIA)
Ohnuma K et al.; “Cord blood transplantation from HLA-mismatched
unrelated donors as a treatment for children with
haematological malignancies”; Br J Haematol 112(4), 981-987;
March 2001 Marco F et al.; “High Survival Rate in Infant
Acute Leukemia Treated With Early High-Dose Chemotherapy and
Stem-Cell Support”; J Clin Oncol 18, 3256-3261; Sept. 15
2000
8.
LEUCEMIA MIELOCITICA ACUTA
(ACUTE MYELOGENOUS LEUKEMIA)
Ohnuma K et al.; “Cord blood transplantation from HLA-mismatched
unrelated donors as a treatment for children with
haematological malignancies”; Br J Haematol 112(4),
981-987; March 2001Gorin NC et al.; “Feasibility and recent
improvement of autologous stem cell transplantation for
acute myelocytic leukaemia in patients over 60 years of
age: importance of the source of stem cells”; Br. J.
Haematol. 110, 887-893; Sept 2000 Bruserud O et al.; “New
strategies in the treatment of acute myelogenous leukemia:
mobilization and transplantation of autologous peripheral
blood stem cells in adult patients”; Stem Cells 18, 343-
351; 2000
9.
LEUCEMIA MIELOCITICA CRONICA
(CHRONIC MYELOGENOUS LEUKEMIA) Ohnuma K et al.; “Cord blood
transplantation from HLA-mismatched unrelated donors as a
treatment for children with haematological malignancies”; Br
J Haematol 112(4), 981-987; March 2001
10.
LEUCEMIA MIELOMONOCITICA INFANTILE
(JUVENILE MYELOMONOCYTIC LEUKEMIA)
Ohnuma K et al.; “Cord blood transplantation from HLA-mismatched
unrelated donors as a treatment for children with
haematological malignancies”; Br J Haematol 112(4), 981-987;
March 2001
11.
LINFADENOPATIA
ANGIOIMMUNOBLASTICA CON DISPROTEINEMIA (ANGIOIMMUNOBLASTIC
LYMPHADENOPATHY with DYSPROTEINEMIA) Lindahl J et al.;
“High-dose chemotherapy and APSCT as a potential cure for
relapsing hemolysing AILD”; Leuk Res 25(3), 267-270; March
2001
12.
MIELOMA MULTIPLO
(MULTIPLE MYELOMA)
Laughlin MJ et al.; “Hematopoietic engraftment and survival
in adult recipients of umbilical-cord blood from unrelated
donors”, New England Journal of Medicine 344, 1815-1822;
June 14, 2001 Vesole, DH et al.; “High-Dose Melphalan With
Autotransplantation for Refractory Multiple Myeloma:
Results of a Southwest Oncology Group Phase II Trial”; J
Clin Oncol 17, 2173-2179; July 1999.
13.
MIELODISPLASIA O SINDROME MIELODISPLASTICA
(MYELODYSPLASIA)
Ohnuma K et al.; “Cord blood transplantation from HLA-mismatched
unrelated donors as a treatment for children with
haematological malignancies”; Br J Haematol 112(4),
981-987; March 2001 Bensinger WI et al.; “Transplantation of
bone marrow as compared with peripheral-blood cells from
HLAidentical relatives in patients with hematologic
cancers”; New England Journal of Medicine 344, 175-181; Jan
18 2001
14.
CANCRO AL SENO
(BREAST CANCER)
Damon LE et al.; “High-dose chemotherapy and hematopoietic
stem cell rescue for breast cancer: experience in
California”; Biol. Blood Marrow Transplant 6, 496-505; 2000
Paquette, RL et al., “Ex vivo expanded unselected peripheral
blood: progenitor cells reduce posttransplantation
neutropenia, thrombocytopenia, and anemia in patients with
breast cancer”, Blood 96, 2385-2390; October, 2000.
Stiff P et al.; “Autologous transplantation of ex vivo
expanded bone marrow cells grown from small aliquots after
high-dose chemotherapy for breast cancer”; Blood 95,
2169-2174; March 15, 2000 Koc, ON et al.; “Rapid
Hematopoietic Recovery After Coinfusion of Autologous-Blood
Stem Cells and Culture-Expanded Marrow Mesenchymal Stem
Cells in Advanced Breast Cancer Patients Receiving High-Dose
Chemotherapy”; J Clin Oncol 18, 307-316; January 2000
15.
NEUROBLASTOMA
Kawa, K et al.; “Long-Term Survivors of Advanced
Neuroblastoma With MYCN Amplification: A Report of 19
Patients Surviving Disease-Free for More Than 66 Months”; J
Clin Oncol 17:3216- 3220; October 1999
16.
LINFOMA NON-HODGKIN
(NON-HODGKIN’S LYMPHOMA)
Tabata M et al.; “Peripheral blood stem cell transplantation
in patients over 65 years old with malignant
lymphoma--possibility of early completion of chemotherapy
and improvement of performance status”; Intern Med 40,
471-474; June 2001 Josting, A; “Treatment of Primary
Progressive Hodgkin’s and Aggressive Non-Hodgkin’s Lymphoma:
Is There a Chance for Cure?”; J Clin Oncol 18, 332-339;
2000 Kirita T et al.; “Primary non-Hodgkin’s lymphoma of the
mandible treated with radiotherapy, chemotherapy, and
autologous peripheral blood stem cell transplantation”; Oral
Surg Oral Med Oral Pathol Oral Radiol Endod. 90, 450-455;
Oct. 2000
Yao M et al.; “Ex vivo expansion of CD34-positive peripheral
blood progenitor cells from patients with non-Hodgkin’s
lymphoma: no evidence of concomitant expansion of
contaminating bcl2/JHpositive lymphoma cells”; Bone Marrow
Transplant 26, 497-503; Sept. 2000
17.
LINFOMA DI HODGKIN
(HODGKIN’S LYMPHOMA)
Peggs KS et al., “Clinical evidence of a
graft-versus-Hodgkin’s-lymphoma effect after
reducedintensity allogeneic transplantion”, Lancet 365,
1934-1941, 4 June 2005 Josting, A; “Treatment of Primary
Progressive Hodgkin’s and Aggressive Non-Hodgkin’s Lymphoma:
Is There a Chance for Cure?”; J Clin Oncol 18, 332-339; 2000
18.
CARCINOMA RENALE
(RENAL CELL CARCINOMA)
Childs R et al., “Regression of Metastatic Renal-Cell
Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood
Stem-Cell Transplantation”, New England Journal of Medicine
343, 750-758; Sept. 14, 2000 Childs, RW; “Successful
Treatment of Metastatic Renal Cell Carcinoma With a
Nonmyeloablative Allogeneic Peripheral-Blood Progenitor-Cell
Transplant: Evidence for a Graft-Versus-Tumor Effect:; J
Clin Oncol 17, 2044-2049; July 1999
19.
VARI TUMORI SOLIDI
(VARIOUS SOLID TUMORS)
Nieboer P et al.; “Long-term haematological recovery
following high-dose chemotherapy with autologous bone marrow
transplantation or peripheral stem cell transplantation in
patients with solid tumours”; Bone Marrow Transplant 27,
959-966; May 2001 Lafay-Cousin L et al.; “High-dose thiotepa
and hematopoietic stem cell transplantation in pediatric
malignant mesenchymal tumors: a phase II study”; Bone Marrow
Transplant 26, 627-632; Sept. 2000 Michon, J and
Schleiermacher, G. “Autologous haematopoietic stem cell
transplantation for paediatric solid tumors”, Baillieres
Best Practice Research in Clinical Haematology 12, 247-259,
March-June, 1999.
Schilder, RJ et al.; “Phase I trial of multiple cycles of
high-dose chemotherapy supported by autologous
peripheral-blood stem cells”; J. Clin. Oncol. 17, 2198-2207;
July 1999
20.
SARCOMA DEI TESSUTI MOLLI
(SOFT TISSUE SARCOMA)
Blay JY et al.; “High-dose chemotherapy with autologous
hematopoietic stem-cell transplantation for advanced soft
tissue sarcoma in adults”; J. Clin. Oncol. 18, 3643-3650;
Nov 1 2000
21.
LINFOISTIOCITOSI EMOFAGOCITICA
(HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS)
Matthes-Martin S et al.; “Successful stem cell
transplantation following orthotopic liver transplantation
from the same haploidentical family donor in a girl with
hemophagocytic lymphohistiocytosis”; Blood 96, 3997-3999;
Dec 1, 2000
22.
MACROGLOBULINEMIA DI WALDENSTROM
(WALDENSTROM’S MACROGLOBULINEMIA)
Anagnostopoulos A et al.; “High-dose chemotherapy followed
by stem cell transplantation in patients with resistant
Waldenstrom's macroglobulinemia”; Bone Marrow Transplant 27,
1027- 1029; May 2001
23.
SINDROME POEMS
(POEMS SYNDROME) O
MIELOMA OSTEOSCLEROTICO
(OSTEOSCLEROTIC MYELOMA)
Dispenzieri A et al., Peripheral blood stem cell
transplantation in 16 patients with POEMS syndrome, and a
review of the literature, Blood 104, 3400-3407, 15 November
2004
24.
MORBO DI PARKINSONG (PARKINSON’S DISEASE) Lévesque M and
Neuman T, “Autologous transplantation of adult human neural
stem cells and differentiated dopaminergic neurons for
Parkinson disease: 1-year postoperative clinical and
functional metabolic result”, American Association of
Neurological Surgeons annual meeting, Abstract #702; 8 April
2002 Love S et al., Glial cell line-derived neurotrophic
factor induces neuronal sprouting in human brain, Nature
Medicine 11, 703-704, July 2005 Gill SS et al.; “Direct
brain infusion of glial cell line-derived neurotrophic
factor in Parkinson disease”; Nature Medicine 9, 589-595;
May 2003 (published online 31 March 2003) See also July 14,
2004 Senate testimony by Dr. Michel Lévesque:
http://commerce.senate.gov/hearings/testimony.cfm?id=1268&wit_id=3670
and Mr. Dennis Turner:
http://commerce.senate.gov/hearings/testimony.cfm?id=1268&wit_id=3676 |